3D printing in medicine is experiencing stable growth even in pandemic times. Irrespective of the crisis, the industrial production of implants and instruments is being continuously optimized. Thanks to industrial FDM technology, the additive manufacturing of patient-specific polymer cranial implants has a disruptive character, as investment and material costs can be significantly reduced compared to conventional manufacturing techniques and alternative materials. Individualized polymer cranial plates today are predominantly made of PEEK, a high-performance polymer that is widely used and accepted in medical manufacturing. Currently, the implants are mostly milled. This means low resource efficiency, as only 10% or less of the processed material is used for the implant. In addition, the investment in hardware and maintenance is much higher compared to an industrial FDM printer. Here, the waste of an implant is around 10% of its own weight, primarily due to the support structures that are necessary in FDM printing.In addition to PEEK as an established material for cranial implants, titanium implants are also manufactured additively. Again, significantly higher investment costs and maintenance costs for the printer contrast with the comparatively low investment in an industrial FDM printer. In summary, industrial FDM printing of implants is an economically attractive solution for MedTech companies compared to titanium printing or polymer milling.